Identifying Biomarkers for Visual Restoration Strategies in NF1-OPGs

Through a combination of established and novel visual function testing methods, this study will define the functional, structural, metabolic, and patient-reported components of NF1-OPG-induced vision loss. Findings are expected to inform the development of future therapies, validate existing models of the disease, and help identify new metrics for evaluating the efficacy of vision restoration treatments, including those developed within the Gilbert Family Foundation’s Vision Restoration Initiative and in both pre-clinical animal models and human clinical trials.