The goal of this project is to better understand NF1-OPG disease progression in two experimental mouse models and to investigate novel therapies to minimize and perhaps even ameliorate vision loss through protecting neurons, promoting axon regeneration, and preventing or reversing aberrant demyelination.
Investigators
Zhigang He, PhD
Boston Children's Hospital
Larry Benowitz, PhD
Boston Children's Hospital
Zhigang He, PhD
Boston Children's Hospital
Larry Benowitz, PhD
Boston Children's Hospital
Current Stage
Discovery
In Vivo Proof of Concept
IND Enabling
Clinical Trial Phase 1
Clinical Trial Phase 2
Clinical Trial Phase 3