Neuroprotection and Optic Nerve Regeneration in a Mouse NF1 OPG Model

The goal of this project is to better understand NF1-OPG disease progression in two experimental mouse models and to investigate novel therapies to minimize and perhaps even ameliorate vision loss through protecting neurons, promoting axon regeneration, and preventing or reversing aberrant demyelination.

Investigators

Zhigang He, PhD

Boston Children's Hospital

Larry Benowitz, PhD

Boston Children's Hospital

Zhigang He, PhD

Boston Children's Hospital

Larry Benowitz, PhD

Boston Children's Hospital

Current Stage

Discovery

Discovery
In Vivo Proof of Concept
IND Enabling
Clinical Trial Phase 1
Clinical Trial Phase 2
Clinical Trial Phase 3